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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6245bd71ce223f4b0324c096a5dbafd8d6d3b4dd9783c2190305237f909e931' 
  AND token = 'w76L2HTxjgTEA68jpgLeFih9GzB7UwT1fR2jUUamuTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}