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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df549d113c33f347323e76753b7b70ad0ef93d206da6e518afaa4a8249cdd642' 
  AND token = 'Qe5+Qa6AfaWO/J0cSwvVQtBbr+J7gSxh1Ud6X4cbjDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}