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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3006a5d1ca628b5c5676d1800795551db3fb9f781c2a5b4d1e9b05d364e72289' 
  AND token = 'm9YWabMCptIUioejVHAXZkYS0yjHgejW2VuuV858kBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}