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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db664bc8313af5b9bc7e4ccd8ed32d47940265322cfde521dccc2382a536369' 
  AND token = '8mc/KL2tK5iwYqJfvJJgB7xvMvsPbTx5oP2uJPa/dgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}