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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc418710f43276d3e4444a465e8ac200d622c6de6e37180c8e0d0ceaf781820f' 
  AND token = 'sxNBYTM2zKeF6HmLxbFm5+FdVQuRqE62JnZ5GTTxGXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}