SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a9c94914f32f629d04c2aeb59cc8addbce30242a874de896a1240be51bde19' 
  AND token = 's9NffndDcFPI69VNmYzN+HsvzdGliYKVpN4ml0zsyuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}