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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa6c1286f2ddb3a76cb8a602164cda4feaa0398b888d54edb3757097489c147' 
  AND token = 'Xe53s+Nx0d6fmIHLYEDlKX8MxuI+H7t4NBlMzDSTotU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}