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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961946e52c1e72c65b6abe59174babbfbfa7369c1b9f44fc88f2c947f46d9c4b' 
  AND token = 'tOL0YepqTw/IdoxSGwozvapL5sGpPhVVdnmCFbQ6hPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}