SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195d1de6f46b7fa37ae365ca63281774fd41185701cb4369fc93b41ded0c5b17' 
  AND token = 'HRitldUSmoJdAJZalcfwh0JD9tl51SFugZ/NmGHcub4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}