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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72e4fc50798fa4dde85392e9d80f20a747aa124ff88c766f57abf72e17ba7e1' 
  AND token = 'tyxUAW8Sbj3HCxlIcTSRBAwrYnho59c68PtJrWmg+kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}