SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25016336d242ccaa0f8580f1f4cc444b9e0eaa69613239418f0ef77d60b4bc6' 
  AND token = 'PewD8SgPsDFMDaCJufudclgcGLpemPcE67wHKmoIE+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}