SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0025b9194ad1fbe261537bcfac9261b8681e326a7f31314d76ee865644be3274' 
  AND token = '8w7ET3ICG9skzupVByY/uiOkJIvfZ6fJDrTpfNxgeYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}