SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e58423abb073c6eb9b685758c6ca3a4530da41e65e2fbc977be9cf98abff076' 
  AND token = 'TIbTfdq01VxIic5pr58tVL7TyM3USfbRZcdruNVu0ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}