SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80f6f971232486d278cb3ea9a2a11b0fcff7129787e1a55f73803da30ed5319' 
  AND token = '+XQIXGovn1Gxk5aLFxtNYuy13VfRqDqmJX1mndtERlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}