SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734dd5a3cb17713ee55453d80e616e27c1d73274813d12f7f582ff144f66c4d2' 
  AND token = 'ITejsAhb2fHvBeHPUOzIkoyVjBqy0sDUOEDUDjNBzoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}