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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43cda657412a84bfcbd643bebf559f4d5d357e33d4732c3cf5c486e8983c5e7' 
  AND token = 'b4r4ZdX4NDdhIJlr6Z2aKIBOHwT2nUj6qPvP7KZ7LKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}