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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1052e93e8e2c60a73ffcc0948147c5a73075ee80650b52dcab3b3292f340af5' 
  AND token = '6Ho29D1qetsOo+kWUTxCNOAFPLIHOHSce+MmUyyYBeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}