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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d53a112e3816d5fa549ac1eb1392ad27809bb3020aada61073c73507a65833' 
  AND token = 'bpTJGEQY0x2+C0nRpeyRpJZ3CEDiM4aoW3SF3koiRYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}