SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f2b513959d6986d1dc23677a09965444c1b97d9fcb754ed476c242b5cb634f' 
  AND token = 'dFJw550s3dpYgyxYkWM/eieoO7gdcx+YJFZ1GqbvHGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}