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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47c11d220a51557b88179f42d860ed724ca6bfa173cba0a584bfcec4a1b2cf7b' 
  AND token = '59e3pe9Jcq0WWerzvERt+TUZw/t+gzR4qiZBkIssp/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}