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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee39bfb37831ed8172405fd69e1e88bb48680c0339d865a7e615b11ebd1d2cfe' 
  AND token = 'FsphDwNfCm3QQha9hY/UXxXTHteup11vdjyJxJmjPIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}