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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04080e9cdf4afdf77b2468813fd8f1c91d3256848442b5b7ede61f8c9fc21af0' 
  AND token = '4nGGkXDQTMlrXFaqmhuk/I6PJpSxKDOowKlci9ECQoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}