SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d03fcdd6d8f3cc8d7c16358b06883f52270483be915f9aec644b45e5c4a27c' 
  AND token = 'pnrBY8dFEqq3J3sp5bBRbpnnF9W8hWA25aeKjShHkq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}