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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c95c9972686e74ca9768e7aa62038b2908d42a4ca1a76d586fb3f49a3e993d4' 
  AND token = 'TE3QvaNNfk6c5vIA4wB4w0pjyhNbsXxriwuuN2PbJlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}