SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecd31318651c953f598361dacd9022f0aa14f7dd62d02a825b290d1210025e0' 
  AND token = 'lnxstmNII9BW1QGMAbsp77UUYZVAWSY1wzTy+suZ3cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}