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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a273426e5c972c2267764cab9701c80994121201c477b631b04bd73500bea6c4' 
  AND token = '70aVgNvUTiwbYbi3R2IrL+q1BGpXsZCQPV6Pkkw7p3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}