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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ecfa54e8d294c2ad899ed513cf7ef2a9dd19fc6d60734a5ad96a028a35298b' 
  AND token = 'Si3aX2G1tForaXfvkXCVQBKWVC9gkXWJdc5tdUsPhrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}