SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4f08715d526884f4f5cacdfa2adc16e7ca2a6b13e4870c164d0e89c3e6a8e9' 
  AND token = 'A7xZYosCiqpjBNXjSno3NFjuQ4ShFUmjGYCWXBXRh0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}