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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ed56f50f4c259fdd8a895721a3c9c17fe32c49a1fa8acf98974d42b5e148ea' 
  AND token = 'jeL5WyoXSmDfta0k8MzAQtTU9bgUbh/WG80vd6X7YO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}