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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d765d12c7a6cb2ec8be3d882f5fc5fe6c6452e758cd07977ea79df44ac56807' 
  AND token = 'puFe0oUMGWAldzp4wg3wDswVEdd3v+bzPTDiSaf1LUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}