SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dc2b3e151c6d4f2a895e2985a87b8974d008eb57d2c88bb443378a9ce918e1' 
  AND token = '/xu2/Bfc4sQ+IVzwYJDvvu+XVR5QJ0CSjNAketsjTz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}