SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc444d997c14a96301bb19d3ff3c0085198418eac05b498931a2a31cb05f762d' 
  AND token = '9GcaK0UKsOQuaraX0gP9VHbgvWj6j1s2joQLwEVqbh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}