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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd3b02ca0f4c1c93fef8abec6897b2440c9944d18db75182d56ae4db4919a53' 
  AND token = 'apiM48Eut0xbAwW+j//+mdNoFpBP9sC3CoN43hvQqjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}