SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb8f5f23824e72b1f9957c43ea385cca8ffc23025c1f3b854f02d0ce4a3a307' 
  AND token = '+7EvYzmz0TxDLbI0GnYUKvrTZh/lZkZn/wm0LV0axrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}