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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d42d9cc62d0b6698d428fe7d3ce5c5486f0189c0eaa41c678c4108f14293799' 
  AND token = 'Lle27/X+fJ/jmE8xZJP5TFs4PUQBNoBr6mLjtof1BDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}