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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2613b5c76edada184cebc09fc0cb137a2b00ab3e8a1cf9c3d3b774ac510440' 
  AND token = 'yWA9sJifD4EpJZgWgVEwHguiV6JMWBFvYtl1ta0Xrx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}