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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c082a155786f0650cca0780a8ef04949857200f7ecb9472e8f952dd82499577' 
  AND token = 'tFHGK9Mdu9+UPOJlZv4lSPv2zeLxmRlMtd4Z25M4pFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}