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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6864bf0b39a5d2e3001a267130e80c9387b7bddc0cd5ceb0ccf3e1059eedf16f' 
  AND token = '28Ejk3Xnff1LWtM3KJgeySeOmjRko5+1t3GEykZfiio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}