SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19eadf8af598750363758e0d95e598c49d906ab1ae07223621db36d7ad9afa3e' 
  AND token = 'q1itMtNSjdvlmRdyqh953GFYIkHAEdCdkMR/5aUnunI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}