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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622ec1c5c5a1be85655473bfbb0b4d74e5d9abc2761e84b53029d095c8d89f34' 
  AND token = 'CiBVI3R9nKqZlyUbq78cSMitKkUELaUPCT6hyDMxNSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}