SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee70afa4ce5a2d51eba8b5017207b8a689118f63ec79e39b8dd45cf642c59a7' 
  AND token = 'SrUsRz2/nKdvpbSVcTf4Z+WSxb6+QiNtyDKix0bJMpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}