SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4478dab4b6f03879654cfb77929181457072005fcc8a10c8df28f88c739fabc' 
  AND token = '/z3Y7aKUOFbCoDXVd01NEeMoDVhVHjIY1nDTMHVTzqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}