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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c42bd4b2d8e3a99a213d6c1893fe321cf5b8280bee1b66b4d867f0a99822136' 
  AND token = 'yDuhJsAY4/X4bV0Ax6nOVkbdxYFki/KpTzvuhMWHi3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}