SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a883c9949428c85d6bc8d41be161649e7fde33bfc0db116ae8054fdb9ec9b1e' 
  AND token = 'PEI6VAgyvoEOBCldP5Xvt6+B9hvGhPQG31NlqZmcVTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}