SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e990a24f75e51b16c0b3e9f28ece8f1600aa4d8ee91748077393462ed144ba42' 
  AND token = 's3YNqDXoIw803AMvQNA+wr5m4Pt2EIBI+woW6fIExLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}