SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00dbbe0b391d49117e347daafd99d15deb45473ffa899430d04289f7769f8d78' 
  AND token = '3MaQ07p4jMx5QByz7vXuKFpzhy0ZESlcEp+BFs0Oc0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}