SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ef873be26dccc9c2f11ab40707e1bf014a442dd7785e3c2a94aad45e6ed0e5' 
  AND token = 'R0XJif8NPZm2Eeo75s7/CN2JLGc1S1Jt3Nj6BKK8VKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}