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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b7bcaae8efbe6deed530d4af08e72b5b0406f48b97926ed63f8c77b6a49341b' 
  AND token = 'QcxHQ+4tDl6e+rEUZ+V6OBEIdx7DCui79bVlOrgTPAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}