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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be148ff74993dc7af55cd8ff5a4600d17379f24a88b6b49a03427144f9f927c' 
  AND token = '8pOyw2fowwya1t8MRUTowcLntmAIq7cxck8P9ZEj1zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}