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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022591600e9bdd9221c9aca42d9c942f88eda8371541049942fe9ec1069d4fb0' 
  AND token = 'Jgldcq2rqil+MZV33p8TOPYe0U2IR3+f93lmPz1zXlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}